Outside of word-of-mouth, is there anything to indicate this isn't simply fat, rather than calcium deposits?
The context in which they appear, at least for me. My girls don't get them until they stop producing eggs, and removing the calcium from the cage makes them go away after a week or so.
removing the calcium from the cage makes them go away
If it's not calcium pockets, it's strange that they'd go away after the calcium has been removed from the cage.
Other than that, nope, I have no proof.
calcium pockets: are they more prevalent among females than males? please enlighten. TIA
Fat also.. cannot dissapear and reappear at the drop of a hat.
What constitutes the drop of a hat? Lipolysis and lipogenesis can occur easily, depending upon environmental influences.
It would not be a protein storage area. Protein isn't stored beyond intracellular free amino acid pools, and that's not really considered storage in the first place as much as a working area for typical cellular processes, often involving ribosomal activity. Excess protein (beyond what can be utilized in a given period for a given demand) is converted to glucose for the most part. The glucose either circulates or is then synthesized into glycogen, depending upon Caloric balance. If glycogen stores are full, then the glucose can be shunted toward triglyceride formation and then that fat will be either used or stored (such as via ASP). Just because fat is stored in the tail doesn't mandate that fat is only stored in the tail. Especially if rate or volume in one depot becomes a bottleneck.
It could easily be some other type of storage area, though, although the ones I have come across were not clear, but white, which is consistent with WAT, however, where pigments begin and end muddies those waters.
What constitutes the drop of a hat? Lipolysis and lipogenesis can occur easily, depending upon environmental influences.
It would not be a protein storage area. Protein isn't stored beyond intracellular free amino acid pools, and that's not really considered storage in the first place as much as a working area for typical cellular processes, often involving ribosomal activity. Excess protein (beyond what can be utilized in a given period for a given demand) is converted to glucose for the most part. The glucose either circulates or is then synthesized into glycogen, depending upon Caloric balance. If glycogen stores are full, then the glucose can be shunted toward triglyceride formation and then that fat will be either used or stored (such as via ASP). Just because fat is stored in the tail doesn't mandate that fat is only stored in the tail. Especially if rate or volume in one depot becomes a bottleneck.
It could easily be some other type of storage area, though, although the ones I have come across were not clear, but white, which is consistent with WAT, however, where pigments begin and end muddies those waters.
I can attest to that!
The bulges are a sign of health - let's just leave it like that!
Please just keep it simple.
You make a valid point, but I think your question has been proved, no one has any other proof then experience and word of mouth. I'm sure most people on here are more concerned with the breeding and general health of their geckos rather then the intricate cellular details of them. So far everyone has said that they believe based out of common logic that these are calcium storage pockets, so whether or not they really on a cellular level, I'm not sure if any one has studied them enough to determine that for fact. However from everyone's general experience, they are indeed a sign of health, but also a sign to cut back on some form of supplementation which often seems to be associated with removal of calcium.
The original question of this post has been answered, but if you want solid proof you are going to have to probably either search else where or conduct studies yourself. I'm sure if you have a genetics question any number of people here could answer with solid fact.
Also when the term "drop of a hat was used" it was meant in an almost literal sense, these pockets will appear one day, and be gone by the next, fat deposits are not capable of that rapid lipogensis, and commonly there is no environmental change.
As far as pigmentation, there seems to be none in these areas, these pockets appear more like a blister having a more watery consistency.
I'd rather keep it accurate.